Remove user's email signature from tickets created by email

When users create a ticket by email, or reply to one by email, their email signature is included every time. This makes the ticket less readable and generally clogs it up.  It would be nice if there was a way, possible through automation, that we could someone identify the email signature and remove it.  For example, one option would be to create hidden HTML elements that and automation rule could detect for the start and end of the signature and remove everything in between. I'm sure there are other ways that this could be accomplished as well.